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Therapeutic Apheresis
Services
Therapeutic apheresis (TA) is a general term describing a
procedure in which blood is removed from a patient as a means of
medical treatment. TA is generally performed to remove harmful
substances from the blood or from a component of the blood.
The blood withdrawal procedure is performed by placing a dual lumen
(dialysis) catheter into the patient’s vein. The catheter is
connected to a machine (which contains a centrifuge) that draws the
blood out and then separates it into red blood cells, white blood
cells, platelets and plasma, the liquid portion of blood. The
healthy components of the blood are returned to the patient, while
the unhealthy components are discarded.
The terms therapeutic apheresis, plasmapheresis and therapeutic
plasma exchange (TPE) are often used interchangeably, but actually
denote different procedures, generally classified as either cell
depletions (such as leukapheresis and plateletpheresis) or blood
component exchanges (such as plasma exchange and red blood cell
exchange). The same type of procedure can be used to collect
Hematopoietic Progenitor Cells, or peripheral blood stem cells, for
the purpose of transplantation in a variety of diseases.
Benefits of Therapeutic Apheresis
Therapeutic apheresis has been successfully used to treat many
hematologic, neurologic, renal, rheumatic, and metabolic
disorders. In most clinical situations, it is used to remove
a pathogenic or toxic macromolecule, such as an antibody, an
abnormal plasma protein, or other substance. The therapeutic
objective is to reduce the circulating levels of these molecules to
ameliorate the disease process.
Therapeutic plasma exchange (TPE) can also be performed to replace
a substance that is normally present in plasma, whose absence is
deleterious to the patient. Many diseases are successfully
treated with a short series of procedures. Chronic regularly
scheduled or intermittent procedures, as needed, may provide
long-term control of other diseases, particularly if drug therapy
is toxic or ineffective.
Most Common Uses
Some of the most common indications include:
• Thrombotic Thrombocytopenic Purpura (TTP)
• Guillain-Barré Syndrome
• Myasthenia Gravis
• Chronic Inflammatory Demyelinating
Polyneuropathy
(CIPD)
• Sickle Cell Disease
• Acute Leukemia
• Many other diseases
These are life threatening conditions in which emergency
therapeutic apheresis (on the ready 24 hours a day) is the primary
mode of acute treatment.:
• Thrombotic Thrombocytopenic Purpura (TTP)
• Acute chest syndrome in sickle cell disease
• Thrombocytosis
• Hyperleukocytosis
• Hyperviscosity
Why Choose FBC?
Florida’s Blood Centers (FBC) experienced and professional staff
provides 24/7 consultation services for all therapeutic apheresis
procedures right at your hospital location—we come to you! Plus,
our Therapeutic Apheresis (TA) staff is specially trained and
focuses primarily on TA and maintain all required state licenses
and certifications.
Our staff are backed by FBC staff physicians who are available for
consultation at all times. FBC’s physicians are Board Certified in
Transfusion Medicine/Blood Banking by the American Board of
Pathology. |
  
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